Paediatric and Adolescent Treatment

Improving HIV Service Delivery for Infants, Children and Adolescents: Towards a framework for collective action

admin — Tue, 28 Jan 2020 19:15:11 +0000

Improving HIV Service Delivery for Infants, Children and Adolescents: Towards a framework for collective action admin Tue, 01/28/2020 - 21:15

In June 2019, UNICEF convened a group of about 40 global experts from 24 organizations and institutions to advance the collective thinking on paediatric HIV service delivery. The aim of this “think tank” consultation was to build consensus on the specific programme interventions that need to be scaled up to improve the quality of HIV treatment services and reach more infants, children and adolescents with these lifesaving medicines.

Participating organizations included:

Aidsfonds
Africaid-Zvandiri
African Network for the Care of Children Affected by HIV/AIDS
(ANECCA)
Baylor College of Medicine
Centers for Disease Control and Prevention (CDC)
Clinton Health Access Initiative (CHAI)
Elizabeth Glaser Pediatric AIDS Foundation (EGPAF)
ELMA Philanthropies
Health Innovations Kenya
FHI 360
ICAP at Columbia University
Joint United Nations Programme on HIV/AIDS (UNAIDS)

Kenya Ministry of Health
Office of the Global AIDS Coordinator (OGAC)
Pact
Pediatric-Adolescent Treatment Africa (PATA)
Positive Action for Children Fund (PACF) / ViiV Healthcare
Réseau Enfants et VIH en Afrique (EVA)
United Nations Children’s Fund (UNICEF)
University of Nairobi
United States Agency for International Development (USAID)
World Health Organization (WHO)
World Council of Churches – Ecumenical Advocacy Alliance (WCC–EAA)
Yale University

Experts addressed the gaps in the continuum of care which are causing children to be missed before they are tested, before they are given their test results and before they are provided with lifelong treatment and care. Read more about the evidence base and the call for action in the brief above.

Paediatric and Adolescent Treatment

Organization Tag

Region Tags

Population Tags

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Health systems strengthening

Maternal, newborn and children health

Policy/Enabling Environment

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Brief

Strategy

Year Tags

2019

Download file(s)

Brief: Improving HIV Service Delivery for Infants Children and Adolescents

Paediatric Service Delivery Framework

cmannikarottu — Tue, 26 Nov 2019 16:54:16 +0000

Paediatric Service Delivery Framework cmannikarottu Tue, 11/26/2019 - 18:54

The paediatric service delivery framework presents strategies to address bottlenecks across the continuum of care for each population: infants, children and adolescents. This includes keeping mothers who receive interventions for the prevention of mother-to-child HIV transmission (PMTCT) and their infants in care; locating missing infants, children and adolescents through family and index testing; linking those diagnosed with HIV to services; treating them with efficacious regimens and retaining them on treatment to achieve viral suppression. It describes comprehensive and targeted service delivery models, which emphasize strong linkages between testing, treatment and care, and between communities and facilities.

The framework was developed by a group of global experts who were convened by UNICEF in June 2019 to advance the collective thinking on paediatric HIV service delivery. The partnership's analysis of current evidence and specific programme interventions that need to be scaled up to improve the quality of HIV treatment services and reach more infants, children and adolescents with these lifesaving medicines is presented here.

The full framework, policy briefs and supporting worksheets are available for download (updated July 2020).

Paediatric and Adolescent Treatment

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Family centred care/services

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Brief

Strategy

Year Tags

2019

Download file(s)

Framework: Improving HIV Service Delivery for Infants, Children and Adolescents (WEB)

Framework: Improving HIV Service Delivery for Infants, Children and Adolescents (PRINT)

Worksheet: Assessing the situation

The Long Walk

eliu — Tue, 23 Jan 2018 14:51:46 +0000

The Long Walk eliu Tue, 01/23/2018 - 16:51

Mentor mothers support and empower pregnant women in protecting their babies from HIV infection and staying healthy.

Paediatric and Adolescent Treatment

Adolescent Prevention

2018

CROI Summary 2017 (Mar 2017)

admin — Wed, 03 May 2017 17:31:04 +0000

CROI Summary 2017 (Mar 2017)

A total of 105 participants from Uganda, Nepal, Iran, Zimbabwe, South Africa, Kenya, and many other countries attended the webinar on March 9th which featured new research on PMTCT and pediatric treatment presented at CROI 2017.

The links to the webinar, presentations, and webinar summary are below:

admin Wed, 05/03/2017 - 20:31

Taxonomy-Programme

PMTCT

Paediatric and Adolescent Treatment

Year Tags

2017

Content Bottom

Presented on March 9, 2017

Global Accelerated Action for the Health of Adolescents (AA-HA!) - Second edition

rlekirkegaard — Mon, 26 Feb 2024 20:26:37 +0000

Global Accelerated Action for the Health of Adolescents (AA-HA!) - Second edition rlekirkegaard Mon, 02/26/2024 - 22:26

This second edition of AA-HA! guidance to support country implementation builds on the first edition published in 2017. It is a collaborative effort spearheaded by the World Health Organization in collaboration with UNAIDS, UNESCO, UNFPA, UNICEF, UN WOMEN, the World Food Programme and PMNCH.

Building on the solid foundation of the first edition and voices of adolescents and young adults around the world, this multi-agency product has evolved to incorporate valuable learnings from the past six years, including of the COVID-19 pandemic's impacts. Latest estimates of mortality and disease burden, updated evidence, and a broader focus on wellbeing make the second edition a cutting-edge resource for policy makers in the area of adolescent health and well-being.

AA-HA! 2.0 offers insights into the current health and well-being landscape of the world’s over 1.2 billion adolescents, underlining evidence-based solutions and presenting strategies for priority setting, planning, implementing, and evaluating health and well-being programmes. The inclusion of key implementation strategies and real-world case studies make this guide a practical tool for governments in designing and implementing a new generation of adolescent health and well-being programmes.

Paediatric and Adolescent Treatment

Adolescent Prevention

Organization Tag

WHO

Region Tags

Global

Population Tags

Adolescents

Topic Tags

Adolescent friendly services

Document Type Tags

Guidance

Year Tags

2023

Paediatric Abacavir/Lamivudine/Dolutegravir (pALD) fixed-dose combination: Introduction and rollout planning considerations for national programmes

rlekirkegaard — Thu, 21 Dec 2023 17:30:23 +0000

Paediatric Abacavir/Lamivudine/Dolutegravir (pALD) fixed-dose combination: Introduction and rollout planning considerations for national programmes rlekirkegaard Thu, 12/21/2023 - 19:30

Dolutegravir (DTG)-based HIV treatment regimens are recommended by the World Health Organization for children living with HIV (CLHIV) who weigh at least 3 kg. In 2020, the United States Food and Drug Administration (US FDA) granted tentative approval of paediatric DTG 10 mg scored, dispersible tablets (pDTG) for CLHIV weighing a minimum of 3 kg and at least four weeks of age. In early 2021, national HIV programmes in low- and middle-income countries (LMICs) began to transition CLHIV from treatment regimens containing non-nucleoside reverse transcriptase inhibitor (NNRTI) and lopinavir/ritonavir to pDTG. As of the last quarter of 2022, at least 73 countries have already placed or received orders for pDTG1 and an estimated 130,000 children have transitioned to pDTG. pDTG currently is administered along with optimised backbone antiretrovirals (ARVs) such as abacavir/lamivudine 120/60 mg scored dispersible tablets (pABC/3TC) per the WHO’s 2021 Consolidated HIV Guidelines.

This brief aims to inform the transition from pDTG + pABC/3TC to the new fixed-dose combination (FDC) dispersible tablet of paediatric ABC/3TC/DTG 60/30/5 mg (pALD).

Paediatric and Adolescent Treatment

Organization Tag

Region Tags

Population Tags

Topic Tags

Paediatric ARVs and formulations

Document Type Tags

Brief

Year Tags

2023

Download file(s)

pALD introduction and rollout planning

Leveraging the Learning from HIV Programming for Pregnant and Parenting Adolescent Girls

rlekirkegaard — Tue, 21 Nov 2023 16:59:01 +0000

Leveraging the Learning from HIV Programming for Pregnant and Parenting Adolescent Girls rlekirkegaard Tue, 11/21/2023 - 18:59

This brief, the first in UNICEF's new Leveraging the Learning series, sets out to leverage the learnings from holistic, integrated, multisectoral, and age- and gender-responsive approaches to respond to and reduce early and adolescent pregnancy, support young mothers, and improve health and well-being outcomes for adolescent girls and their children.

Highlighting promising practices for pregnant adolescents living with HIV, the report is relevant for efforts to support all pregnant adolescent girls, regardless of their HIV status.

Paediatric and Adolescent Treatment

Adolescent Prevention

Organization Tag

UNICEF

Region Tags

Global

Population Tags

Adolescents

Topic Tags

Adolescent friendly services

Adolescents living with HIV

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Year Tags

Download file(s)

Leveraging the Learning: Insights from HIV Programming for Pregnant and Parenting Adolescent Girls

Ending the AIDS Epidemic Among Young People in the Middle East and North Africa

rlekirkegaard — Thu, 16 Nov 2023 15:50:48 +0000

Ending the AIDS Epidemic Among Young People in the Middle East and North Africa rlekirkegaard Thu, 11/16/2023 - 17:50

THIS REPORT IS FORTHCOMING AND WILL BE PUBLISHED JANUARY 2024.

This report examines the HIV epidemic and response among young people, including key populations, in the Middle East and North Africa, using both quantitative and qualitative data. It focuses on marginalized young people who are highly exposed to various health risks but not reached with information, services and tools.

Paediatric and Adolescent Treatment

Adolescent Prevention

Organization Tag

UNICEF

Region Tags

Middle East and North Africa

Population Tags

Adolescents

Key affected populations

Topic Tags

Adolescent and young key populations

Document Type Tags

Advocacy

Global and regional report

Year Tags

2023

Getting back on track to ending AIDS in Children

rlekirkegaard — Thu, 16 Nov 2023 12:45:57 +0000

Getting back on track to ending AIDS in Children rlekirkegaard Thu, 11/16/2023 - 14:45

In this viewpoint Getting back on track to ending AIDS in Children: It could just be easier than you think, published in the Journal of the International AIDS Society on World Children's Day, 20 November 2023, UNICEF reviews the global inequities faced by children and adolescents living with HIV and highlights three strategies to end AIDS in children by 2030.

Paediatric and Adolescent Treatment

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Download file(s)

Ending AIDS in Children - JIAS Viewpoint on World Children's Day 2023

Understanding Viral Load Suppression Trends (2017-2020) for Children Living with HIV in Eastern and Southern Africa

admin — Tue, 05 Sep 2023 20:58:40 +0000

Understanding Viral Load Suppression Trends (2017-2020) for Children Living with HIV in Eastern and Southern Africa admin Tue, 09/05/2023 - 23:58

In 2022 an estimated 930,000 children (aged 0-14 years) were living with HIV in Eastern and Southern Africa. Nearly one-third of these children were not receiving lifesaving treatment. Children with HIV need both antiretroviral treatment and viral load suppression if they are to lead long and healthy lives.

UNICEF, in collaboration with governments and partners, supported an updated analysis of laboratory information management systems (LIMS) data in Malawi, Uganda and Zimbabwe from 2017-2020 to better understand viral suppression among children, especially in the context of WHO recommendations for newer, more efficacious drug regimens and the COVID-19 pandemic.

A previous analysis of 2016-2018 LIMS data found that one in every three children was not virally suppressed. The updated study found a steady increase since then in viral load testing, the use of more efficacious and palatable antiretroviral regimen options, and improved viral load suppression. However, children are still falling short of global targets to end AIDS by 2030. The full report describes the methodology, key findings, limitations, and proposes further prioritization and accelerated action to improve treatment outcomes for children with HIV.

Paediatric and Adolescent Treatment

Organization Tag

UNICEF

Region Tags

Eastern and Southern Africa

Population Tags

Document Type Tags

Year Tags