Sixteen years of progress since the International AIDS Conference was last held in Durban. Millions of lives saved. But to end the AIDS epidemic there are new milestones to reach, barriers to break and frontiers to cross.

The Global Plan towards the elimination of new HIV infections among children by 2015 and keeping their mothers alive (Global Plan) has been operational at country level for the past four years. It prioritizes the 22 countries that, in 2009, accounted for 90% of the global number of pregnant women living with HIV who were in need of services to prevent mother-to-child transmission. This report presents country performance in 2014 and is based on country-developed models using Spectrum software (see “A note on measurement” at the end of the document).

This National Guidelines for Management of HIV and AIDS 5th edition 2015 has taken into consideration the WHO 2013 Consolidated guidelines recommendations of antiretroviral drugs for treating and preventing HIV infection on the use. It provide details on antiretroviral therapy for adults, children, and pregnant and breastfeeding women. In addition, it provides details on the use of ARV drugs (what to do) and operational aspects (how to do it) along the cascade of HIV-care related services.

Our world is also waking up to the reality now that for us to win the fight towards an AIDS free generation, we must fiercely combat TB. What is making the need to double our efforts even more pressing is the growing threat of strains of the disease that do not respond to most antibiotics (multi-drug resistant TB or MDR-TB). The overlap of TB and HIV is a deadly combination with tragic consequences. TB is the leading killer of people with HIV, accounting for one in four HIV-related deaths. Globally, one-third of people living with HIV are also infected with TB, and if left unchecked and untreated, TB can kill a person with HIV/AIDS in a matter of weeks.

This third edition of the Malawi Guidelines for Clinical Management of HIV in Children and Adults will be implemented starting May 2016. It replaces all previous editions of the Malawi Antiretroviral therapy (ART) and Prevention of Mother to Child Transmission (PMTCT) guidelines. This document is written for medical doctors, clinical officers, medical assistants, nurses, midwives, health surveillance assistants (HSAs) and medical records clerks who are working in public and private sector health facilities in Malawi. It is designed to be a practical guide for implementation of integrated HIV Services.

This 2016 version of the Zambia Consolidated Guidelines for Treatment and Prevention of HIV Infection provides simplified guidance on a continued approach that positively affects the continuum of HIV care, while adding to innovative methods that will reduce transmission rates and increase life span for those on treatment. This is all to further accelerate efforts to meet the ambitious Fast-Track target for 2020, including achieving major reductions in the number of people dying from HIV-related causes and the 90–90–90 treatment target.

The implementation of the National HIV and AIDS Strategic Plan 2010/11–2014/15 enabled the country to continue its progress towards universal access to HIV and AIDS services. The National HIV and AIDS Strategic Plan 2015/2016 –2019/2020 (NSP) will build on the previous efforts, pursuing the same objective, with inspiration from the global targets of “Zero new HIV infections, Zero HIV-related deaths and Zero stigma and discrimination due to HIV”.

As Tanzania strives to reach middle income status, the health sector has resolved to give more attention to the quality of health services in tandem with the pursuit of universal access. At the same time, better health for the entire population will be promoted through the adoption of health in all policies. The overall objective of HSSP IV is to reach all households with essential health and social welfare services, meeting, as much as possible, the expectations of the population, adhering to objective quality standards, and applying evidence-informed interventions through efficient channels of service delivery.

These integrated HIV Management Guidelines provide the standards and recommendations to move Swaziland forward in achieving the Government of the Kingdom of Swaziland’s vision of zero new infections and ending AIDS. To achieve this vision we need a concerted effort from all stakeholders and at all levels of service delivery to translate these guidelines into action while ensuring delivery of quality services and efficient use of limited resources.

The new consolidated guidelines provide standardized, simplified and less toxic drug combinations harmonized for the management of Prevention of Mother to Child Transmission (PMTCT), children, adolescents and adults with HIV/AIDS, TB and other common opportunistic infections. It will provide guidance for clinicians, managers and trainers on the use of available regimens within the context of continuum of HIV comprehensive care for prevention, treatment and support for all age groups in private and public sector to realize our vision of a long and healthy life for all citizens. This approach will also ensure that people living with HIV are started on the right regimen at the right time.